Local Anesthetic
Sleep Dart explodes when it hits, slowing enemies and dealing 45 damage over 3 seconds.
Choose this when
Choose this when you can land Sleep Dart on a diving enemy and need the slow to create distance. It requires the dart to hit.
The ally receiving Nano Boost moves 30% faster, helping them close the distance to enemies.
Ana's rifle normally deals the same damage even on a headshot, but this perk enables critical hits.
See when an alternative fits better.
Sleep Dart explodes when it hits, slowing enemies and dealing 45 damage over 3 seconds.
Choose this when you can land Sleep Dart on a diving enemy and need the slow to create distance. It requires the dart to hit.
Nano Boost increases both Ana's and her target's movement speed by 30%.
The ally receiving Nano Boost moves 30% faster, helping them close the distance to enemies. Ana also moves 30% faster, which helps her reposition or escape immediately after using her ultimate. There is no hit requirement, so the speed increase does not depend on aim.
Biotic Grenade bounces after its first explosion and explodes again. The second blast deals 60 damage and provides 60 healing.
Choose this on maps with frequent team fights where allies and enemies cluster together, or when you need to focus on healing without time to aim for heads.
Biotic Rifle can deal critical damage to enemies.
Ana's rifle normally deals the same damage even on a headshot, but this perk enables critical hits. It helps finish distant enemies or enemies put to sleep by Sleep Dart. You need to hit their head to benefit, so the alternative is more consistent if you are not confident in your aim.
We checked perk effects, values and conditions against game data, then reviewed the reasons and alternatives. These recommendations interpret when the effects are useful; they are not claims of playtesting every hero. Game data reviewed: 2026-10-12.
English text reviewed: 2026-10-12